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Maguire R、Cowie J、Leadbetter C、McCall K、Swingler K、McCann LA 和 Kearney N (2009) 开发用于接受辅助化疗的乳腺癌患者的副作用风险评估工具 (ASyMS©-SERAT)。护理研究杂志,14 (1),第 27-40 页。 https://doi.org/10.1177/1744987108099235
摘要Patients with breast cancer receiving chemotherapy are at risk of developing toxicities which can be severe or life threatening. The aim of this study was to develop and test a side effect risk modeling tool (ASyMS©-SERAT) for use in patients with breast cancer undergoing adjuvant chemotherapy. The study was conducted in two phases. Phase 1 entailed the development of the ASyMS©-SERAT tool using a secondary data set and in collaboration with an expert group of clinicians and an advisory group of patients. In phase 2, the predictive accuracy of the tool was measured using a prospective data set of 24 patients with breast cancer undergoing adjuvant chemotherapy. A high level of accuracy was reported for four of the six symptoms measured (>70%) 支持 ASyMS©-SERAT 在预测化疗相关毒性方面的未来开发和应用。对于患者来说,此类信息可用于确定他们可能经历的副作用的目标信息,从而有助于根据他们的个人需求提供量身定制的信息。对于临床医生来说,了解潜在副作用的可能性可以帮助他们识别出现某些毒性风险更大的患者,从而促进更有针对性和更具成本效益的干预措施。
关键字乳腺癌;化疗;预测风险模型;症状;癌症研究;癌症预防;乳腺癌治疗;癌症化疗
期刊护理研究杂志:第 14 卷,第 1 期
状态 | 已发布 |
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发布日期 | 31/01/2009 |
网址 | http://hdl.handle.net/1893/1035 |
发布商 | 圣人 |
ISSN | 1744-9871 |
eISSN | 1744-988X |
人 (1)
计算机科学教授